|
KMID : 1123920100240010096
|
|
Korean Journal of Oriental Physiology and Pathology
2010 Volume.24 No. 1 p.96 ~ p.101
|
|
|
Effect of Artemisiae Argi Folium Fermented with Sacchromyces Cerevisiae on Hydrogen Peroxide Production of Human Hepatocyte Treated with Toxicants
|
|
Park Wan-Su
|
|
|
Abstract
|
|
|
|
The purpose of this study is to investigate the effect of water extract from Artemisiae Argi Folium Fermented with Sacchromyces cerevisiae (AFS) on hydrogen peroxide production within human hepatocyte HepG2 cells treated with gallic acid, EtOH, nicotine, acetaminophen, and acetaldehyde. AFS (0~400 ug/mL) was treated with gallic acid, EtOH, nicotine, acetaminophen, and acetaldehyde. And the intracellular productions of hydrogen peroxide were measured by dihydrorhodamine 123 (DHR) assay. AFS showed the restoration of the intracellular productions of hydrogen peroxide which were reduced by gallic acid, EtOH, nicotine, acetaminophen, and acetaldehyde in HepG2 Cells. AFS could be supposed to have the hepatoprotective effect related with hepatocytologic signaling activity against gallic acid, EtOH, nicotine, acetaminophen, and acetaldehyde.
|
|
|
KEYWORD
|
|
|
hepatocyte, Sacchromyces cerevisiae, artemisiae argi folium, fermentation, hydrogen peroxide
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|
|